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Risk Factors for Stevens-Johnson Syndrome

Posted On February 2nd, 2021 By CSSFIRM.COM

Stevens-Johnson Syndrome (SJS) is a disorder that affects the skin, mucous membranes, genitals, and eyes. In some cases, SJS is caused by uncontrollable circumstances or conditions. However, other risk factors are usually adverse reactions to certain medications, and occasionally caused by some type of infection. The medicines that most commonly cause SJS include:

  • Allopurinol
  • Carbamazepine
  • Lamotrigine
  • Nevirapine
  • Meloxicam
  • Piroxicam
  • Phenobarbital
  • Phenytoin
  • Sulfa antibiotics
  • Sertraline
  • Sulfasalazine

Conditions That Might Lead to SJS

There are certain conditions and circumstances that make some people more at risk for contracting medication-induced SJS. These include:

  • Viral infections like herpes, hepatitis, viral pneumonia, or HIV.
  • A weakened immune system due to HIV or AIDS, lupus or other autoimmune conditions, and certain treatments like chemotherapy and organ transplants.
  • A previous history of Stevens-Johnson syndrome caused by medication makes a person at risk for a reoccurrence should they take the same drug or a drug from the same family of medications again.
  • A family history of Stevens-Johnson syndrome, such as a close family member that has had the condition.
  • Specific genes. Chinese people with the HLA B1502 gene have been found to be at greater risk for developing SJS after taking carbamazepine.

SJS typically begins with flu-like symptoms, followed by a painful red or purple rash that rapidly spreads and forms blisters. Eventually, the affected skin will die and peel off. SJS is considered a medical emergency that requires hospitalization, often in intensive care or a burn unit.

Stevens-Johnson Syndrome Linked to Allopurinol Use: Common treatment for Gout

How is Stevens-Johnson Syndrome Diagnosed?

SJS is usually diagnosed by a skin specialist, who bases the diagnosis on a physical examination, the patient’s symptoms, and medical history – specifically medications taken recently. To confirm the diagnosis, a small skin sample (biopsy) may be taken and tested in a laboratory. As soon as an SJS diagnosis is made, any medications that may be causing the condition should immediately be stopped.

Contact our attorneys a Childers, Schlueter & Smith for a free consultation at. You might be entitled to bring forth a claim against the manufacturer of the medication you believes has caused you injury. For more in depth information click HERE.

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